Dozens of Pagans Motorcycle Club members and associates were arrested and charged with drug trafficking.
Federal officials say that a total of 30 members of the violent motorcycle gang were arrested in western Pennsylvania following a two year-long investigation.
US attorney Scott Brady said that the gang used violence to control cocaine, heroin and meth trafficking in that part of the state.
Raids involving 300 federal agents resulted in the seizure of 12 guns, $28,000 in cash, jewellery and “significant quantities” of drugs.
Mr Brady said that the Pagans are one of the most violent motorcycle gangs in the US and the FBI estimates they have more than 1,500 members across 41 chapters.
All 30 Pagans are now in federal custody.
“This takedown is the most recent victory in our fight to disrupt and dismantle